The recent research work of our Department team has focused on the issue of cell size variation and the impact of this variability on other phenotypic traits of an organisms. We are particularly interested in the relationship between trace elements, cell size and oxidative stress as well as the link connecting the genome mass, cell size and energy metabolism of animals. The results obtained in our laboratories indicate that cell size, through the intensity of apoptosis and proliferation processes, is also a feature that can shape seasonal changes in the body mass of small mammals. No less intriguing are the research conducted in our department on the borderline of physiology and toxicology, and in particular the role of toxicity of cadmium and other metals in verte- and invertebrates. Currently, as a new project, we are conducting several studies on the relationship between the basal metabolic rate and the probability of developing serious diseases that nowadays constitute the largest percentage of deaths on the globe, including cancer and diabetes.
- Evaluation of the mechanisms of the development rate of liver cancer in laboratory mice artificially selected for high and low BMR.
- Examination of the mechanisms responsible for the development of insulin resistance and type 2 diabetes in the context of metabolic rate differentiation.
- Examination of adaptations of small mammals (bank vole) to seasonal changes in climatic conditions.
- Examination of the mechanisms responsible for seasonal changes in body and organ weight in the bank vole.
- Examination of the mechanisms of seasonal plasticity of cell size in the bank vole.
- The relationship between trace elements, cell size and oxidative stress in the bank vole.
Cooperation with international and Polish scientific institutions:
1. Department of Experimental Pharmacology, Medical University of Białystok, Poland
2. Institute of Environmental Sciences, Jagiellonian University in Kraków, Poland
In the Department of Physiology and Histology weconduct several lectures and laboratories for students of Biology as: Animal’s Physiology, Histology, Developmental Biology, Cell Biology;
Selected BSc theses:
Theoretical models of metabolic rate scaling in animals;
Does the Peto paradox solution exist?;
Marihuana – a medicine or a drug?
Why do we feel pain? - the formation and significance of pain
Selected MSc theses:
Development rate of the liver cancer in mice selected for high and low basal metabolic rate.
Cell size and oxidative stress in breeding bank vole females
Wyślij je na stronę internetową Wydziału Biologiczno-Chemicznego.